General nonlinear sieve learnings are classes of nonlinear sieves that can approximate nonlinear functions of high dimensional variables much more flexibly than various linear sieves (or series). This paper considers general nonlinear sieve quasi-likelihood ratio (GN-QLR) based inference on expectation functionals of time series data, where the functionals of interest are based on some nonparametric function that satisfy conditional moment restrictions and are learned using multilayer neural networks. While the asymptotic normality of the estimated functionals depends on some unknown Riesz representer of the functional space, we show that the optimally weighted GN-QLR statistic is asymptotically Chi-square distributed, regardless whether the expectation functional is regular (root-$n$ estimable) or not. This holds when the data are weakly dependent beta-mixing condition. We apply our method to the off-policy evaluation in reinforcement learning, by formulating the Bellman equation into the conditional moment restriction framework, so that we can make inference about the state-specific value functional using the proposed GN-QLR method with time series data. In addition, estimating the averaged partial means and averaged partial derivatives of nonparametric instrumental variables and quantile IV models are also presented as leading examples. Finally, a Monte Carlo study shows the finite sample performance of the procedure

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

With the development of gene sequencing technology, an explosive growth of gene data has been witnessed. And the storage of gene data has become an important issue. Traditional gene data compression methods rely on general software like G-zip, which fails to utilize the interrelation of nucleotide sequence. Recently, many researchers begin to investigate deep learning based gene data compression method. In this paper, we propose a transformer-based gene compression method named GeneFormer. Specifically, we first introduce a modified transformer structure to fully explore the nucleotide sequence dependency. Then, we propose fixed-length parallel grouping to accelerate the decoding speed of our autoregressive model. Experimental results on real-world datasets show that our method saves 29.7% bit rate compared with the state-of-the-art method, and the decoding speed is significantly faster than all existing learning-based gene compression methods.

As a powerful representation of 3D scenes, the neural radiance field (NeRF) enables high-quality novel view synthesis from multi-view images. Stylizing NeRF, however, remains challenging, especially on simulating a text-guided style with both the appearance and the geometry altered simultaneously. In this paper, we present NeRF-Art, a text-guided NeRF stylization approach that manipulates the style of a pre-trained NeRF model with a simple text prompt. Unlike previous approaches that either lack sufficient geometry deformations and texture details or require meshes to guide the stylization, our method can shift a 3D scene to the target style characterized by desired geometry and appearance variations without any mesh guidance. This is achieved by introducing a novel global-local contrastive learning strategy, combined with the directional constraint to simultaneously control both the trajectory and the strength of the target style. Moreover, we adopt a weight regularization method to effectively suppress cloudy artifacts and geometry noises which arise easily when the density field is transformed during geometry stylization. Through extensive experiments on various styles, we demonstrate that our method is effective and robust regarding both single-view stylization quality and cross-view consistency. The code and more results can be found in our project page: https://cassiepython.github.io/nerfart/.

Neural Radiance Fields (NeRF) have demonstrated superior novel view synthesis performance but are slow at rendering. To speed up the volume rendering process, many acceleration methods have been proposed at the cost of large memory consumption. To push the frontier of the efficiency-memory trade-off, we explore a new perspective to accelerate NeRF rendering, leveraging a key fact that the viewpoint change is usually smooth and continuous in interactive viewpoint control. This allows us to leverage the information of preceding viewpoints to reduce the number of rendered pixels as well as the number of sampled points along the ray of the remaining pixels. In our pipeline, a low-resolution feature map is rendered first by volume rendering, then a lightweight 2D neural renderer is applied to generate the output image at target resolution leveraging the features of preceding and current frames. We show that the proposed method can achieve competitive rendering quality while reducing the rendering time with little memory overhead, enabling 30FPS at 1080P image resolution with a low memory footprint.

Motion prediction is highly relevant to the perception of dynamic objects and static map elements in the scenarios of autonomous driving. In this work, we propose PIP, the first end-to-end Transformer-based framework which jointly and interactively performs online mapping, object detection and motion prediction. PIP leverages map queries, agent queries and mode queries to encode the instance-wise information of map elements, agents and motion intentions, respectively. Based on the unified query representation, a differentiable multi-task interaction scheme is proposed to exploit the correlation between perception and prediction. Even without human-annotated HD map or agent's historical tracking trajectory as guidance information, PIP realizes end-to-end multi-agent motion prediction and achieves better performance than tracking-based and HD-map-based methods. PIP provides comprehensive high-level information of the driving scene (vectorized static map and dynamic objects with motion information), and contributes to the downstream planning and control. Code and models will be released for facilitating further research.

We present a simple yet effective end-to-end Video-language Pre-training (VidLP) framework, Masked Contrastive Video-language Pretraining (MAC), for video-text retrieval tasks. Our MAC aims to reduce video representation's spatial and temporal redundancy in the VidLP model by a mask sampling mechanism to improve pre-training efficiency. Comparing conventional temporal sparse sampling, we propose to randomly mask a high ratio of spatial regions and only feed visible regions into the encoder as sparse spatial sampling. Similarly, we adopt the mask sampling technique for text inputs for consistency. Instead of blindly applying the mask-then-prediction paradigm from MAE, we propose a masked-then-alignment paradigm for efficient video-text alignment. The motivation is that video-text retrieval tasks rely on high-level alignment rather than low-level reconstruction, and multimodal alignment with masked modeling encourages the model to learn a robust and general multimodal representation from incomplete and unstable inputs. Coupling these designs enables efficient end-to-end pre-training: reduce FLOPs (60% off), accelerate pre-training (by 3x), and improve performance. Our MAC achieves state-of-the-art results on various video-text retrieval datasets, including MSR-VTT, DiDeMo, and ActivityNet. Our approach is omnivorous to input modalities. With minimal modifications, we achieve competitive results on image-text retrieval tasks.

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true capabilities on sparse, irregularly sampled, multivariate, and imbalanced physiological data are not yet fully explored. In this paper, we systematically examine the performance of machine learning models for the clinical prediction task based on the EHR, especially physiological time series. We choose Physionet 2019 challenge public dataset to predict Sepsis outcomes in ICU units. Ten baseline machine learning models are compared, including 3 deep learning methods and 7 non-deep learning methods, commonly used in the clinical prediction domain. Nine evaluation metrics with specific clinical implications are used to assess the performance of models. Besides, we sub-sample training dataset sizes and use learning curve fit to investigate the impact of the training dataset size on the performance of the machine learning models. We also propose the general pre-processing method for the physiology time-series data and use Dice Loss to deal with the dataset imbalanced problem. The results show that deep learning indeed outperforms non-deep learning, but with certain conditions: firstly, evaluating with some particular evaluation metrics (AUROC, AUPRC, Sensitivity, and FNR), but not others; secondly, the training dataset size is large enough (with an estimation of a magnitude of thousands).

Aspect-based sentiment analysis (ABSA) aims at extracting opinionated aspect terms in review texts and determining their sentiment polarities, which is widely studied in both academia and industry. As a fine-grained classification task, the annotation cost is extremely high. Domain adaptation is a popular solution to alleviate the data deficiency issue in new domains by transferring common knowledge across domains. Most cross-domain ABSA studies are based on structure correspondence learning (SCL), and use pivot features to construct auxiliary tasks for narrowing down the gap between domains. However, their pivot-based auxiliary tasks can only transfer knowledge of aspect terms but not sentiment, limiting the performance of existing models. In this work, we propose a novel Syntax-guided Domain Adaptation Model, named SDAM, for more effective cross-domain ABSA. SDAM exploits syntactic structure similarities for building pseudo training instances, during which aspect terms of target domain are explicitly related to sentiment polarities. Besides, we propose a syntax-based BERT mask language model for further capturing domain-invariant features. Finally, to alleviate the sentiment inconsistency issue in multi-gram aspect terms, we introduce a span-based joint aspect term and sentiment analysis module into the cross-domain End2End ABSA. Experiments on five benchmark datasets show that our model consistently outperforms the state-of-the-art baselines with respect to Micro-F1 metric for the cross-domain End2End ABSA task.

User-generated-content (UGC) videos have dominated the Internet during recent years. While many methods attempt to objectively assess the quality of these UGC videos, the mechanisms of human quality perception in the UGC-VQA problem is still yet to be explored. To better explain the quality perception mechanisms and learn more robust representations, we aim to disentangle the effects of aesthetic quality issues and technical quality issues risen by the complicated video generation processes in the UGC-VQA problem. To overcome the absence of respective supervisions during disentanglement, we propose the Limited View Biased Supervisions (LVBS) scheme where two separate evaluators are trained with decomposed views specifically designed for each issue. Composed of an Aesthetic Quality Evaluator (AQE) and a Technical Quality Evaluator (TQE) under the LVBS scheme, the proposed Disentangled Objective Video Quality Evaluator (DOVER) reach excellent performance (0.91 SRCC for KoNViD-1k, 0.89 SRCC for LSVQ, 0.88 SRCC for YouTube-UGC) in the UGC-VQA problem. More importantly, our blind subjective studies prove that the separate evaluators in DOVER can effectively match human perception on respective disentangled quality issues. Codes and demos are released in https://github.com/teowu/dover.